good question i slow drip kalk and supplement mag on a regular schedule i add 3 caps every other day or so and i also supplement iodide and strontium once a week and what i notice is that my mushrooms triple in size the day after even though they usually go back to their size within a couple of day's
it doesn't deplete it, but it will cause usuage of it, your dosing cAl and alk with the kalk and magnesium will be used up. doing kalk you will still need to dose mag