Scientists Develop Blowfish Minus Poison
By Mari Yamaguchi
Associated Press
June 9, 2004
TOKYO - Blowfish has long been a delicacy only for the adventurous: every year in Japan, a few people are poisoned to death eating it. Now scientists have put a school of pufferfish on a special diet and come up with a version that tastes just like the real thing — without the lethal consequences.
"It's nice and soft," gushed Osamu Arakawa, a marine biologist heading the project at Nagasaki University. "As sashimi, you dip it in a citrus-flavored soy sauce — it's delicious."
Eating pufferfish — known in Japanese as "fugu" — is not always so carefree. The powerful poison tetrodotoxin is found in the ovaries, liver and intestines, and only specially licensed chefs are qualified to prepare the fish for human consumption.
Still, fugu remains a final meal for some. Three diners died in Japan in 2003 from pufferfish poisoning after preparing the dish at home, according to government figures.
Researchers in Nagasaki, in southern Japan, are getting over that potentially deadly hurdle by examining the fish's diet.
"We believe that pufferfish acquire poison by eating poisonous food, such as starfish and shellfish, rather than producing it themselves. So we fed them nonpoisonous food," Arakawa said.
He and his colleagues kept about 5,000 fugu on a strict regime of mackerel and other nonpoisonous food at seven locations along Japan's west coast from 2001 to 2003.
They also raised their specimens in water at least 10 yards above the seafloor or in purified tanks to minimize their exposure to toxins.
Poisonless pufferfish, fed only mackerel and other nonpoisonous food, swim in a circulatory tank filled with filtered sea water at Fisheries Ecology Research Center run by seafood restaurant Manbou Co. in the southern Japanese fishing town of Yobuko in this photo taken in January 2003. Blowfish, known in Japanese as 'fugu,' has long been a delicacy only for the adventurous: every year in Japan, a few people are poisoned to death eating it. Now scientists have put a school of pufferfish on a special diet and come up with a version without the lethal consequences. (AP Photo/Manbou Co.)
Arakawa says it worked. For two years, the group examined the fish every month, and they all tested negative for tetrodotoxin each time.
The fish has not yet gone into mass production for sale, but it's already causing a stir.
Some in the tourist industry are ready to promote the new fugu. A hot springs resort near Nagasaki is trying to obtain a special government permit to allow hotels and restaurants to serve the liver — normally the most lethal part of the fish.
Japanese health officials are cautious.
"The finding is a great scientific achievement, but it does not immediately mean we can guarantee food safety," said Masanori Imagawa, a Health Ministry official. "When it comes to fugu, we can't afford any mistakes."
The fish could draw some diners who have long wanted to try fugu but feared the poison. Its meat is firm and light when served raw as sashimi, and succulent when cooked in a stew.
But some pufferfish fans are sure to balk. For many, the brush with death is part of the allure of the meal, and some diners go as far as indulging in the liver — though not until the poison has been soaked out.
Takeshi Yamasuge, a fugu restaurant owner near Tokyo, chuckled when asked about poison-less fugu.
He said his customers prefer the real thing, despite hefty prices that go as high as 25,000 yen ($230) per kilogram (2.2 pounds).
"Nontoxic fugu is boring," he declared. "Fugu is exciting because it's toxic."
http://story.news.yahoo.com/news?tm...p/20040609/ap_on_sc/japan_poisonless_blowfish
By Mari Yamaguchi
Associated Press
June 9, 2004
TOKYO - Blowfish has long been a delicacy only for the adventurous: every year in Japan, a few people are poisoned to death eating it. Now scientists have put a school of pufferfish on a special diet and come up with a version that tastes just like the real thing — without the lethal consequences.
"It's nice and soft," gushed Osamu Arakawa, a marine biologist heading the project at Nagasaki University. "As sashimi, you dip it in a citrus-flavored soy sauce — it's delicious."
Eating pufferfish — known in Japanese as "fugu" — is not always so carefree. The powerful poison tetrodotoxin is found in the ovaries, liver and intestines, and only specially licensed chefs are qualified to prepare the fish for human consumption.
Still, fugu remains a final meal for some. Three diners died in Japan in 2003 from pufferfish poisoning after preparing the dish at home, according to government figures.
Researchers in Nagasaki, in southern Japan, are getting over that potentially deadly hurdle by examining the fish's diet.
"We believe that pufferfish acquire poison by eating poisonous food, such as starfish and shellfish, rather than producing it themselves. So we fed them nonpoisonous food," Arakawa said.
He and his colleagues kept about 5,000 fugu on a strict regime of mackerel and other nonpoisonous food at seven locations along Japan's west coast from 2001 to 2003.
They also raised their specimens in water at least 10 yards above the seafloor or in purified tanks to minimize their exposure to toxins.

Poisonless pufferfish, fed only mackerel and other nonpoisonous food, swim in a circulatory tank filled with filtered sea water at Fisheries Ecology Research Center run by seafood restaurant Manbou Co. in the southern Japanese fishing town of Yobuko in this photo taken in January 2003. Blowfish, known in Japanese as 'fugu,' has long been a delicacy only for the adventurous: every year in Japan, a few people are poisoned to death eating it. Now scientists have put a school of pufferfish on a special diet and come up with a version without the lethal consequences. (AP Photo/Manbou Co.)
Arakawa says it worked. For two years, the group examined the fish every month, and they all tested negative for tetrodotoxin each time.
The fish has not yet gone into mass production for sale, but it's already causing a stir.
Some in the tourist industry are ready to promote the new fugu. A hot springs resort near Nagasaki is trying to obtain a special government permit to allow hotels and restaurants to serve the liver — normally the most lethal part of the fish.
Japanese health officials are cautious.
"The finding is a great scientific achievement, but it does not immediately mean we can guarantee food safety," said Masanori Imagawa, a Health Ministry official. "When it comes to fugu, we can't afford any mistakes."
The fish could draw some diners who have long wanted to try fugu but feared the poison. Its meat is firm and light when served raw as sashimi, and succulent when cooked in a stew.
But some pufferfish fans are sure to balk. For many, the brush with death is part of the allure of the meal, and some diners go as far as indulging in the liver — though not until the poison has been soaked out.
Takeshi Yamasuge, a fugu restaurant owner near Tokyo, chuckled when asked about poison-less fugu.
He said his customers prefer the real thing, despite hefty prices that go as high as 25,000 yen ($230) per kilogram (2.2 pounds).
"Nontoxic fugu is boring," he declared. "Fugu is exciting because it's toxic."
http://story.news.yahoo.com/news?tm...p/20040609/ap_on_sc/japan_poisonless_blowfish