If you read the article from the think tank, there is absolutely no ramifications from missing a dose or for that matter several doses. For that matter, if I were to go on vacation I would absolutely have to have somebody do routine things to my reef, wouldn't I? Who is going to empty my skimmer? Feed my tank? I would not go on vacation and leave my reef unattended no matter how automated the system. I venture to say, neither would anybody else. So on my list of things that need be done, I will leave doses of the vodka pre-measured in syringes. I'm not going to get into how much I dose now because it's too lengthy. It is in the thread at RC. The same way you have to determine how many cups of pellets to run by water volume is how the vodka dose is calculated. Right now I am on a maintainace dose of 10 ml per day, 5ml in am and 5ml in pm. As for crashing my reef, not going to happen. You don't indescriminatly throw vodka in your tank. It is a slow, measured process. Honestly, think about it, WHERE did the idae for these bio-pellets arise? Do you think they thought of carbon dosing on their own? No, they read about and know that people had been carbon dosing their reefs for years and if the results had not been proven, would they have put the time and money into developing a carbon source they could sell? Of course not. I am open-minded to the pellets and the idea behind it. I just believe there is a lot more research and time needed to judge them. Why can't you be open-minded? The best decisions come from respecting each other's opinions, drawing the benefits and detriments of each opinion and coming up with the best conclusion. I think you will see, in time, that this bio-pellet technology will change in many different ways if it is to survive.